Can I Give My Dog Denamarin?
Published range by weight
| Weight | SAMe + milk thistle (silybin) (published range) |
|---|---|
| 10 lb dog | 82-91 mg |
| 25 lb dog | 204-227 mg |
| 50 lb dog | 408-454 mg |
| 75 lb dog | 612-680 mg |
Computed from the published 18-20 mg/kg reference range, every 24h. Product strengths rarely split evenly, so round DOWN to the nearest practical dose and confirm with your vet.
Cats use a different amount
The published cat reference (90 mg SAMe (small-size product) per cat) differs from the dog range. Never split the difference between species; check the cat page instead.
About SAMe + milk thistle (silybin)
SAMe + milk thistle (silybin) is a supplement rather than a drug, which still deserves the same dosing care. You will see it sold as Denamarin, generic combos and store-brand equivalents, and the label strength on the box is what matters for the math, not the brand. Reference data on this page reflects published veterinary sources, not a prescription for your dog.
What to have ready when you call the vet
Whether you are confirming a dose or reporting that your dog already got into something, the call goes faster with four facts ready: your dog's current weight, the exact product name and strength from the label, how much was given or eaten, and roughly when. With those, most clinics can answer in one call.
The safe habit
Confirm any medication decision with your veterinarian, who knows your dog's health history and other medications. VetDose shows published reference data, not prescriptions.